Anti-HTT Antibody, clone MW8,100UG,MABN2529-100UG,Sigma

销售价: ¥ 4180.79 / 件
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订货号 0BW1673
品牌型号 Sigma MABN2529-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

347.6 kDa calclulated
HD exon-1 67Q aggregate.


Application

Immunocytochemistry Analysis: A representative lot detected HTT in Immunocytochemistry applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Immunohistochemistry Analysis: A representative lot detected HTT in Immunohistochemistry applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Western Blotting Analysis: A representative lot detected HTT in Western Blotting applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Enzyme Immunoassay (ELISA) Analysis: A representative lot detected HTT in ELISA applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Immunoprecipitation Analysis: A representative lot immunoprecipitated HTT in Immunoprecipitation applications (Baldo, B., et. al. (2012). Chem Biol. 19(2):264-75).

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected HTT in Tissue lysate of 9 month-old WT or Q140 KI HD mice.


Biochem/physiol Actions

Clone MW8 is a mouse monoclonal antibody that detects Huntingtin protein. It targets an epitope within nine amino acids in the exon-1 region.


Physical form

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Isotype testing: Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG2a.


Other Notes

Human, Mouse.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
antibody formpurified antibody
cloneMW8,monoclonal
purified byusing protein G
species reactivitymouse, human
concentration (Please refer to lot specific datasheet.)
technique(s)ELISA: suitable,immunocytochemistry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable
isotypeIgG2aκ
UniProt accession no.P42858
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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