- 商品介绍
- 规格参数
- 包装参数
Application
Gallamine triethiodide has been used:
- as a relaxant for measuring spinal trigeminal nucleus recordings from single neurons.
- as an antagonist in neuroblastoma cells as M2 receptor
- to reduce eye movement during retinal surgery in rat
Biochem/physiol Actions
Gallamine triethiodide has anti-muscarinic effect. It is a competitive antagonist for the muscarinic receptor. Gallamine is regarded as neuromuscular blocking agent.
Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
吸湿
| Quality Level | 200 |
| assay | ≥98% (TLC) |
| form | powder |
| mp | 235 °C (dec.) (lit.) |
| solubility | H2O: 100 mg/mL,ethanol: soluble |
| storage temp. | 2-8°C |
| SMILES string | [I-].[I-].[I-].CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC |
| InChI | 1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9H3;3*1H/q+3;;;/p-3 |
| InChI key | REEUVFCVXKWOFE-UHFFFAOYSA-K |
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146) |
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