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Biochem/physiol Actions
RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways. RHC 80267 is generated by the hydrolysis of phosphatidylinositol (PI) and bPC by phospholipase C (PLC). DAG mediates the actions of a large number of hormones and cytokines by activating protein kinase C (PKC). A sustained elevation in intracellular DAG may cause neoplastic transformation.
RHC 80267 is a diacylglycerol (DAG) lipase inhibitor.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| color | white |
| solubility | DMSO: 9 mg/mL |
| SMILES string | O=C(NCCCCCCNC(=O)O\N=C1/CCCCC1)O\N=C2/CCCCC2 |
| InChI | 1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26) |
| InChI key | RXSVYGIGWRDVQC-UHFFFAOYSA-N |
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