- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6)
SIRT6-IN-1 (2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)−1,2,3,4-tetrahydroquinazoline-6-sulfonamide) is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6). It improves glucose tolerance in a type 2 diabetes mouse model. SIRT6-IN-1 delays experimental autoimmune encephalomyelitis disease onset in mice.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear (Warmed) |
| storage temp. | -10 to -25°C |
| SMILES string | [S](=O)(=O)(Nc3ccc(cc3)Oc4cnccc4)c1cc2c([nH][c]([nH][c]2=O)=O)cc1 |
| InChI | 1S/C19H14N4O5S/c24-18-16-10-15(7-8-17(16)21-19(25)22-18)29(26,27)23-12-3-5-13(6-4-12)28-14-2-1-9-20-11-14/h1-11,23H,(H2,21,22,24,25) |
| InChI key | CNILPKOOBRBNEQ-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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