Protein Kinase Cν (PKCν) Active human,5UG,P7123-5UG,Sigma

销售价: ¥ 8141.09 / 件
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订货号 0BN1753
品牌型号 Sigma P7123-5UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 °C using a final concentration of 50 μM [32P] ATP.


Biochem/physiol Actions

PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.


Physical form

Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol


技术参数 Specifications
recombinantexpressed in E. coli
Quality Level200
assay≥75% (SDS-PAGE)
formbuffered aqueous glycerol solution
mol wtprotein apparent mol wt ~142 kDa
UniProt accession no.O94806
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... PRKD3(23683)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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