Anti-DHODH Antibody,100UG,ABC138,Sigma

销售价: ¥ 4409.16 / 件
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订货号 0BV3017
品牌型号 Sigma ABC138
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Dihydroorotate oxidase (DHODH) is also called Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase). DHODH is a member the dihydroorotate dehydrogenase (Type 2) family and is involved in pyrimidine biosynthesis. DHODH catalyzes the conversion of dihydroorotate to orotate using quinone as an electron acceptor. DHODH defects can cause postaxial acrofacial dysostosis (POADS).
~43 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.


Immunogen

Epitope: Topological Domain ( Mitochondrial intermembrane)
KLH-conjugated linear peptide corresponding to the Topological Domain (Mitochondrial intermembrane) of human DHODH.


Application

Anti-DHODH Antibody is a rabbit polyclonal antibody, validated for use in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected DHODH in human testis and breast carcinoma sections.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional


Biochem/physiol Actions

Other Homologies: Rat (93% sequence homology) and Mouse (86% sequence homology).
This antibody recognizes the Topological Domain (Mitochondrial intermembrane) of DHODH.


Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Control
T47D cell lysate
Evaluated by Western Blotting in T47D cell lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected DHODH in 10 µg of T47D cell lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
purified byaffinity chromatography
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin),western blot: suitable
NCBI accession no.NP_001352
UniProt accession no.Q02127
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... DHODH(1723)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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