- 商品介绍
- 规格参数
- 包装参数
Immunogen
CASK-GST fusion protein (amino acids 318-415).
Application
Research Sub Category
Synapse & Synaptic Biology
Anti-CASK Antibody, clone K56A is an antibody against CASK for use in WB, IC, IH.
Research Category
Neuroscience
Western blot: 1 μg/mL
Immunocytochemistry: 0.5-1.0 μg/mL
Immunohistochemistry on 4% paraformaldehyde fixed tissue: 0.5- 1.0 μg/mL
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
CASK. The immunogen protein represents a CASK-specific domain that lies between the calmodulin binding and PDZ domains. MAB5230 exhibits a specific reaction to the two alternatively spliced isoforms of CASK present in the mammalian CNS, the CASK-B or long (~900 amino acid) isoform present in rat brain membrane preparations, and the soluble CASK-A or short (~600 amino acid) isoform.CASK is a synapse-associated Ca2+/calmodulin-dependent protein kinase that also contains PDZ, SH3 and guanylate kinase domains. CASK is thought to play a critical role in synaptic vesicle exocytosis and synaptic junctions.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.
Preparation Note
Maintain at 2-8°C in undiluted aliquots up to 6 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | K56A, monoclonal |
| species reactivity | rat, human, mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable,immunohistochemistry: suitable,western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_003688.1 |
| UniProt accession no. | O14936 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... CASK(8573) rat ... Cask(29647) |
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