- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Cell penetrant, potent and highly selective degrader of STAT5A and STAT5B isoforms.
AK-2292 is a cell penetrant, potent and highly selective PROTAC degrader of STAT5A (signal transducer and activator of transcription 5 A) and STAT5B isoforms. AK-2292 potently induces degradation of STAT5 in normal mouse tissues and human chronic myeloid leukemia (CML) xenografts in mice. It potently inhibits the growth of acute myeloid leukemia (AML) cell lines.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
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¥ 2019.57
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¥ 1956.41
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¥ 8135.09
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¥ 2883.61
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¥ 20380.83
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¥ 1586.69
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¥ 4476.05
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¥ 67162.32
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¥ 26022.64
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¥ 37675.92
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¥ 17652.29
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¥ 15894.19
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¥ 108621.02
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